Randomised trial of switching from prescribed non-selective non-steroidal anti-inflammatory drugs to prescribed celecoxib. The Standard care versus Celecoxib Outcome Trial (SCOT)
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چکیده
Citation for published version: MacDonald, TM, Hawkey, CJ, Ford, I, McMurray, JJV, Scheiman, J, Hallas, J, Findlay, E, Grobbee, DE, Hobbs, FDR, Ralston, S, Reid, DM, Walters, MR, Webster, J, Ruschitzka, F, Ritchie, LD, Perez-Gutthann, S, Connolly , E, Greenlaw, N, Wilson, A, Wei, L & Mackenzie, IS 2016, 'Randomised trial of switching from prescribed non-selective non-steroidal anti-inflammatory drugs to prescribed celecoxib. The Standard care versus Celecoxib Outcome Trial (SCOT)' European Heart Journal., 10.1093/eurheartj/ehw387
منابع مشابه
Randomized trial of switching from prescribed non-selective non-steroidal anti-inflammatory drugs to prescribed celecoxib
Citation for published version: MacDonald, TM, Hawkey, CJ, Ford, I, McMurray, JJV, Scheiman, JM, Hallas, J, Findlay, E, Grobbee, DE, Hobbs, FDR, Ralston, SH, Reid, DM, Walters, MR, Webster, J, Ruschitzka, F, Ritchie, LD, Perez-Gutthann, S, Connolly, E, Greenlaw, N, Wilson, A, Wei, L & Mackenzie, IS 2016, 'Randomized trial of switching from prescribed non-selective non-steroidal anti-inflammator...
متن کاملRandomized trial of switching from prescribed non-selective non-steroidal anti-inflammatory drugs to prescribed celecoxib: the Standard care vs. Celecoxib Outcome Trial (SCOT)
Background Selective cyclooxygenase-2 inhibitors and conventional non-selective non-steroidal anti-inflammatory drugs (nsNSAIDs) have been associated with adverse cardiovascular (CV) effects. We compared the CV safety of switching to celecoxib vs. continuing nsNSAID therapy in a European setting. Method Patients aged 60 years and over with osteoarthritis or rheumatoid arthritis, free from est...
متن کاملMethodology of a large prospective, randomised, open, blinded endpoint streamlined safety study of celecoxib versus traditional non-steroidal anti-inflammatory drugs in patients with osteoarthritis or rheumatoid arthritis: protocol of the standard care versus celecoxib outcome trial (SCOT)
INTRODUCTION Cyclooxygenase 2 (COX-2) inhibitors have less upper gastrointestinal toxicity than traditional non-steroidal anti-inflammatory drugs (NSAIDs). However, both COX-2 inhibitors and traditional NSAIDs may be associated with adverse cardiovascular side effects. Data from randomised and observational studies suggest that celecoxib has similar cardiovascular toxicity to traditional NSAIDs...
متن کاملClinical Efficacy of Celecoxib with and without Caffeine versus Ibuprofen for Pain Control following Crown Lengthening Surgery
Objective: Non-steroidal anti-inflammatory drugs (NSAIDs) are the most commonly prescribed pain control medications following periodontal surgery. This study aimed to compare the efficacy of three drug regimens namely celecoxib, celecoxib + caffeine and ibuprofen for pain relief following crown lengthening surgery. Methods: This randomized, double blind clinical trial was performed on 45 pa...
متن کاملPrimary care Differences in outcomes of patients with congestive heart failure prescribed celecoxib, rofecoxib, or non-steroidal anti-inflammatory drugs: population based study
Objectives To compare the risk of death and recurrent congestive heart failure in elderly patients prescribed celecoxib, rofecoxib, or non-steroidal anti-inflammatory drugs (NSAIDs) and to determine whether there are class differences between celecoxib and rofecoxib. Design Population based retrospective cohort study. Setting Databases of hospital discharge summaries and prescription drug claim...
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